Monthly Archives: February 2017

We thank Mari Koivisto, Department of Biostatistics, University of Turku, Finland for help with the statistical analyses. Conflict of interest statement: AK has participated as a member in advisory boards of Pfizer, GlaxoSmithKline and Novartis and received honorarium from these. … Continue reading →

Sílvio Sanches Veiga for the Alexa 488 anti-mouse immunoglobulin G. This work was supported by MEK inhibitor Fapemig and Fundação Araucária/PPSUS (11403/192). Conflict of interest statement: The authors declare that this research was conducted in the absence of any commercial … Continue reading →

, 2013). Comprehensive smoke-free policies have high levels of public support and have been associated with substantial health benefits (Fong et al., 2006, International Agency for Research on Cancer, 2009 and Tang et al., 2003). These include reduced tobacco consumption and increased … Continue reading →

The literature suggests that health professionals need to undertake cross-cultural communication training to improve their interpersonal skills for interacting with Indigenous people, to encourage greater respect towards Indigenous culture and to help understand the dissonant world views of health and … Continue reading →

MRI demonstrated a lack of recurrent tumor up to 1 year following surgery (Fig. 1A). Neurological side effects of this therapy were moderate and resolved within 3 months. The treated dog experienced transient focal neurologic signs that became more severe … Continue reading →

The SPADI has since been used in both primary care on mixed diagnosis (Beaton et al 1996, MacDermaid et al 2006) and surgical patient populations including rotator cuff disease (Ekeberg et al 2008), osteoarthritis, and rheumatoid arthritis (Christie et al … Continue reading →

Cerebral ischaemia is a powerful inducer of the UPR [37], and subjecting JEG-3 cells to hypoxia-reoxygenation causes phosphorylation of eIF2α [25]. This situation may be made worse by changes in posture, which in the bipedal human can influence uterine blood … Continue reading →

This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. The recommended initial dose of donepezil is 5 mg taken once daily. Donepezil is well absorbed with a relative oral bioavailability of 100% and … Continue reading →

Western blots were probed using murine sera raised to recombinant proteins based on the individual MSP1 block 2 types [11] and [15]. Bound antibody was detected with horseradish peroxidase-conjugated rabbit anti-mouse secondary antibody (DAKO), and bands visualized using 5 ml per blot of … Continue reading →

The study protocol was approved by the ethics committee of the Helsinki University Central Hospital and the Finnish Medicines Agency. The study protocol was registered in the International Standard Randomised Controlled Trial Number Register (ISRCTN68125331). Written informed consent was obtained … Continue reading →