The dose of PAF from a previous study Etoposide Etopophos on the hypoglycaemic Chemical effect K Body weight was calculated salvianolic S Acid B measured every week, and extract the required amount by the weight of the rats set. After I 12 h, blood samples from the tail vein on days14 and 28 were collected, and FBG were measured using Accu Chek II born adventage. On day 28 all rats get through the technique of a broken neck following an I Tet Not 12 h, and blood samples were collected for total cholesterol, triglycerides, blood urea and creatinine determined on a spectrophotometer UV9100 using commercial kits. Insulin has been in fasting blood sugar tested using a commercial kit on a 6100 SN immunity t to g-radiation. The index t Insulinsensitivit was using the following formula: in ISI. The statistical analysis. Results were expressed as mean values SD. The statistical significance of differences was determined by analysis of variance by Dunnett’s t-test, followed 鈥 檚 evaluated. A value of p0.05 was considered statistically significant. PAF was analyzed by HPLC and five polyphenolic constituents in the HPLC chromatogram were identified by comparison with corresponding authentic standards, the S Acid salvianic A Protokatechus Acid, rosemary Acid B and A. salvianolic S Salvianolic acid view of insulin sensitization was reported tanshinones PAF danshen subjected to HPLC analysis of tanshinones, tanshinone IIA and Cryptotanshinone and have been identified. The results showed that there confinement no chromatographic peaks of the lipophilic constituents, Lich Cryptotanshinone and tanshinone IIA, and the UV absorption spectrum screw PAF was Similar to S Acid B and tanshinone au Subjected OUTSIDE Cryptotanshinone IIA salvianolic, which revealed that No other tanshinones in the PAF. Effect of polyphenol Acids
the proportion of K Rpergewichts There was no significant CHANGE OF basal group K Body weight of rats. However, at the end of the experiment, increases HTES K Body weight of normal rats 368.629.6 391.023.6 g to g significantly decreased from the 362.933.1 332.742.5 g to g in diabetic rats. Compared with the study DCThis was developed to assess the effect of antidiabetic agents, the proportion of total polyphenol Acids of danshen in diabetic rats by Ern Currency rate rich in fats and low dose of STZ induced. To our knowledge this is the first demonstration that PAF has a positive effect on the improvement of hyperglycemia Anemia, hypo-lipid Mix and has insulin resistance in diabetic rats. To the candidate compounds in the PAF-w Ren Greenhouse to kl, Two selective HPLC methods performed to the tanshinones and polyphenol Acids analyze respectively. It has been shown that phenol acids The main components of the PAF were, were w During Tanshinone compounds in danshen with effective awareness reported by insulin is not recognized. These results provide an important basis for the anti-diabetic effects of PAF and suggest that the total polyphenol Acids in danshen k can be responsible For their pharmacological effects. The H Height of the fasting blood sugar in diabetic rats has been ma Decisively by the oral treatment of PAF reduced the direct detection of T Tigkeitsbereich antihyperglyk Mix PAF. In addition, the level permitted by law.
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