We used event-related functional magnetic resonance imaging [fMRI] to investigate brain areas involved in maintaining and updating the postural representations of the upper limb that participate in the control of reaching movements. We demonstrate that the neural correlates for executing memory-guided reaching movements to unseen target locations that were defined by arm posture, are primarily within regions of the superior parietal lobule [SPL]: including an area of the medial SPL identified as the human homologue of the ‘parietal reach region’ [PRR]. Using
effective connectivity analyses we show that signals that influence the BOLD response within this area originate within premotor areas of the frontal lobe, including premotor AZD5153 solubility dmso cortex and the supplementary motor area. These data are consistent with the view that the SPL maintains an up-to-date estimate of the current postural configuration of the arm that is used during the H 89 manufacturer planning and execution of reaching movements. (C) 2010 Elsevier Ltd. All rights reserved.”
“Intravenous leiomyoma is a benign smooth muscle cell tumor of uterine origin
that may grow into the pelvic veins and the inferior vena cava. It usually affects premenopausal women and the majority (90%) are parous. Because cardiac involvement is present in up to 10% of cases, it may be misdiagnosed as a primary cardiac tumor or a venous thrombus-in-transit. We describe a case of intravascular leiomyomatosis with cardiac extension and the morphological particularities of the removed tumor. (J Vasc Surg 2010;51:1000-2.)”
“Transient Epileptic Amnesia (TEA) is a form of temporal lobe epilepsy associated with ictal and interictal memory disturbance. Some patients with TEA exhibit Accelerated Long-term Forgetting CALF), in which memory for verbal and non-verbal learn more material is retained
normally over short delays but fades at an unusually rapid rate over days to weeks. This study addresses three questions about ALF in TEA: (i) whether real-life events undergo ALF in a similar fashion to laboratory-based stimuli; (ii) whether ALF can be detected within 24h; (iii) whether procedural memories are susceptible to ALF. Eleven patients with TEA and eleven matched healthy controls wore a novel, automatic camera. SenseCam, while visiting a local attraction. Memory for images of events was assessed on the same day and after delays of one day, one week, and three weeks. Forgetting of real-life events was compared with forgetting of a word list and with performance on a procedural memory task. On the day of their excursion, patients and controls recalled similar numbers of primary events, associated secondary details (contiguous events, thoughts and sensory information) and items from the word list.
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