1 (340) 11 9 (219) 1 00 1 53 (0 80, 2 92)

5 88 1 00 1 58

1 (340) 11.9 (219) 1.00 1.53 (0.80, 2.92)

5.88 1.00 1.58 (0.85, 2.93) Low 6.1 (179) 18.9 (196) 0.81 (0.36, 1.84) 2.98 (1.58, 5.61) (0.15–229.65; 1.31–26.43) 0.79 (0.36, 1.73) 2.60 (1.44, 4.72) High High 11.0 (373) 20.8 (448) 1.00 1.79 (1.15, 3.71) 0.55 1.33 (0.76, 2.34) 2.32 (1.39, 3.88) Low 19.9 (136) 25.2 (274) 2.07 (1.16, 3.71) 2.03 (1.26, 3.26) (0.24–1.28; 0.39–0.78) 2.92 (1.53, 5.55) 2.71 (1.58, 4.68) Women Low High 12.3 (268) 25.7 (148) 1.00 1.62 (0.90, 2.91) 1.16 1.00 1.68 (0.95, 2.99) Low 17.1 (269) 28.3 (286) 1.39 (0.80, 2.41) 2.17 (1.29, 3.63) (0.40–3.35; 0.75–1.79) 1.50 (0.88, INCB28060 manufacturer 2.56) 2.30 (1.40, 3.78) High High 17.8 (225) 33.0 (261) 1.00 2.27 (1.41, 3.65) 1.04 1.06 (0.61, 1.84) 2.43 (1.48, 3.97) Low 20.3 (197) 37.8 (429) 1.22 (0.71, 2.10) 2.55 (1.64, 3.99) (0.51–2.12; 0.78–1.40) 1.22 (0.70, 2.13) 2.69

(1.70, 4.27) CI confidence interval aReference group: high job VEGFR inhibitor control and high social support at work in low and high job demands groups. History of psychosocial work characteristics, age, education, origin of country, marital status, family-to-conflict, number of days on sick leave, stress from outside-work problems, worry due to family members, and health conditions at baseline (musculoskeletal disorder, chronic diseases, and self-reported poor health) were all controlled for bReference group: high job control, high social support at work, and low job demands. The aforementioned covariates were all controlled for The results of the sensitivity analyses in the relatively https://www.selleckchem.com/products/prt062607-p505-15-hcl.html unhealthy sample (i.e., alternative study group 2, n = 2,296) were different, particularly in women, from those in the relatively healthy sample (i.e., study subjects of this study). In men, the combination of low job control and low social support at work was a significant risk factor for psychological distress, regardless of the level of job Nintedanib (BIBF 1120) demands. The synergy indexes (80% CIs) between job control and social support at work in men were 2.76 (0.70–10.93) when job

demands were low and 0.62 (0.43–0.91) when job demands were high. In women, they were 0.76 (0.35–1.64) and 0.79 (0.53–1.18), respectively. The combination of low job control and low social support at work was a significant risk factor for psychological distress only when job demands were high. Discussion This cross-sectional study supported partially in men and fully in women a synergistic interaction effect between job control and social support at work on general psychological distress, which was hypothesized based on the collective control concept. A significant excessive risk increase for general psychological distress was observed when workers had both low job control and low social support at work in both men and women when the level of job demands was low.

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