CONCLUSION: Oxygen supply had a significant effect on cell growth and catalytic activity of C.parapsilosis catalyzing asymmetric oxidoreduction. By conveniently controlling agitation in cultivation, cell activity and key enzymes production for a complex reaction of concurrent tandem oxidation and reduction processes can easily be conducted, which could help to cultivate cells catalyzing synthesis of interested chiral compounds. (C) 2008 Society of Chemical Industry”
“The case of a 26 year-old woman with high grade spondylolisthesis, history of diastematomyelia and tethered cord, with acute onset
of back pain and bilateral sciatica after a fall. This comment will focus on three issues: indication for surgery, indication for reduction and levels to be included
in fusion. Surgery is indicated in this case for intermittent urinary incontinence VX-770 mw and saddle anesthesia, and failure of conservative treatment to control pain. Other important determinant of surgical indication is risk of progression, depending rather on the degree of dysplasia as classified by Marchetti-Bartolozzi than on the degree of slip as classified by Meyerding. High dysplastic olisthesis is identified by excessive pelvic retroversion. Reduction is indicated in patients with high torque AZD5582 through L5-S1. L5 severity index (SI) correlates with the magnitud of torque through L5-S1. Similarly, the decision to include L4 in fusion can be made based on the value
of SI for L4.”
“Bariatric surgery is now widely accepted for treatment of morbid obesity. This study compared the effects of laparoscopic sleeve gastrectomy (LSG) and laparoscopic adjustable gastric banding (LAGB) on excess weight loss (EWL) and type 2 diabetes mellitus (T2DM). PubMed and Embase were searched for publications concerning LAGB and LSG from 2000 to 2012, with the last search on August 17, 2012. EWL and T2DM improvement over 6 and 12 months were pooled and compared by meta-analysis. Odds ratios (ORs) and mean differences were calculated with 95 % confidence intervals (CIs). Eleven studies involving 1,004 patients met the inclusion criteria. Compared with LAGB, LSG achieved greater EWL. Sotrastaurin purchase The mean percentage EWL for LAGB was 33.9 % after 6 months in six studies and 37.8 % after 12 months in four studies; for LSG, EWL was 50.6 % after 6 months and 51.8 % after 12 months in the same studies. LSG was also superior to LAGB in treating T2DM. In five studies, T2DM was improved in 42 of 68 (61.8 %) patients after LAGB and 66 of 80 (82.5 %) after LSG, representing a pooled OR of 0.34 (95 % CI 0.16-0.73) and pooled mean differences of -12.55 (95 % CI -15.66 to -9.43) and -4.97 (95 % CI -7.58 to -8.36), respectively. LSG is more effective than LAGB in morbid obesity, with higher percentage EWL and greater improvement in T2DM.
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