There were a number of other occasions of exuberant joy as we unv

There were a number of other occasions of exuberant joy as we unveiled new secrets,

especially our realization that there is a critical period of development early in the life of cats and monkeys. D.H.: I’m always impressed Screening Library by the importance of luck in a career. Many of the decisions I’ve made were matters of luck rather than deliberate planning. My preparation early on, in maths and physics, was determined by my enjoyment of these fields, the fun of doing problems as opposed to memorizing facts. So I think that to be guided by what one enjoys is perhaps the most important thing in deciding what to do by way of preparation. I ultimately decided not to go on with mathematics because of a feeling that to make it in that field required a virtuosity (like becoming a concert pianist) that I probably lacked. And at McGill in wartime the physics department was far too depleted and my undergraduate training was too weak. T.W.: David and I always felt more like explorers of an unknown universe rather than proper scientists. We started out with no hypothesis but just forged ahead to the best of our intuition. It was like taking the thread of new insights one after the other and rolling it up into a great big ball. It is difficult to consider a very different

approach, particularly since we had such a great time during our years of collaboration. My first choice if starting anew would be to explore the 3-MA solubility dmso cortical processing Carnitine dehydrogenase of auditory information. There must be secrets to unearth in exploring the neural basis of our perception of language, music, and voice. Of course, there are many other areas in brain science with rich opportunities for discoveries. My dream is to again be at the starting gate. D.H.: In fact, we did not train so many postdocs or graduate students. Those we had, we left alone for the most part, to train themselves (as we had been trained). We were often lucky in our choices. T.W.: We actually did not train

many students. We had a total of only six graduate students and perhaps a dozen postdoctoral students over our 20 years together at Harvard Medical School. We always did our own experiments from start to finish. The graduate students had their own laboratory space and equipment, and they had to propose their own thesis problems. The postdocs worked on their own projects. We never put our names on any of our student papers. We were lucky in attracting such excellent students, and giving them independence from the beginning worked well in the short and long run. D.H.: The main changes in how science is practiced, in my field, are in my opinion for the worse. I see the main leaders of scientific groups, in my field, spending most of their time in their offices, writing grant requests or papers, or advising their trainees, rather than being engaged in the science that they trained to do.

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