Competing interests All of the authors declared that they had no competing interests. Authors’ contributions CR-f was fully in charge of the study, involved in the design, demonstration, implementation, data collection and statistical analysis, and manuscript composition. WL-q was involved in the design, surveillance and manuscript revising for important intellectual content. HL-s
was involved in writing the manuscript. HL-s and ZJ-b were coordinated the data collection and implementation. All the authors read and approved Inhibitors,research,lifescience,medical the final manuscript. Acknowledgements We would like to appreciate everyone who contributed to the study: all the enrolled patients, the Inhibitors,research,lifescience,medical staff of the participating emergency departments and the researchers and nurses who helped with the data collection. Declarations This article has been published as part of BMC Emergency Medicine Volume 13 Supplement 1, 2013: Proceedings of the 2012 Emergency Medicine Annual Congress. The full contents of the supplement are available online at http://www.biomedcentral.com/bmcemergmed/supplements/13/S1. The publication costs for this article was funded by Naval General Hospital, Beijing 100048, China.
For the same group of animals under the same parameter conditions, in the control group, perfusion images over
Inhibitors,research,lifescience,medical time did not change significantly (Figure (buy Cyclopamine Figure1),1), indicating the lung Inhibitors,research,lifescience,medical perfusion in good condition. In paraquat group, perfusion image color changed the most (Figure (Figure2),2), indicating that lung perfusion
changed significantly over time, suggesting poor lung perfusion and heavy tissue damage. Ulinastatin intervention group image changes were slightly smaller than paraquat group (Figure (Figure3),3), indicating that the lung perfusion changed slightly, suggesting that lung injury was lighter. Comparison of middle and lower lung level CTP parameters from the same rabbit showed that differences among Inhibitors,research,lifescience,medical paraquat group, control group and ulinastatin intervention group were statistically significant (P <0.05), shown in Table Table11. Figure 1 From left to right, CTP images of crotamiton the same rabbit in control group at 2h, 4h, 6h time points, respectively. There were no significant changes, indicating good lung perfusion and no lung injury. Figure 2 From left to right, CTP images of the same rabbit in paraquat group at 2h, 4h, 6h time points, respectively. The color changed most, indicating that pulmonary perfusion changed significantly over time, suggesting heavy lung tissue damage. Figure 3 From left to right, CTP images of the same rabbit in Ulinastatin intervention group at 2h, 4h, 6h time points, respectively. The image changes were slightly smaller than paraquat group, indicating that the lung perfusion changed slightly, suggesting that …
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