Laboratories and monitors provide medical data for processing, and depending on the priority, the results are sent to the patients�� bedside terminal, the physicians�� tablet or e-mail address. The UCHS (Ubiquitous Context-Aware Healthcare Service System) [11] context-aware decision support system uses RFID sensors to sense users life vital signal, such as electrocardiogram (ECG/EKG), heart rate (HR), respiratory rate (RR), blood pressure (BP), blood sugar (BS), temperature and light. Medical expert suggestions are translated into a medical ontology, which provides users requirements inference and a relative services search in a UDDIrepository by a semantic inference engine.
Similarly, CAMPH (Context-Aware Middleware for Pervasive Home Care) [12] offers several key-enabling system services that consist of P2P-based context query processing, context reasoning for activity recognition and context-aware service management. It can be used to support the development and deployment of various home care services for the elderly, such as patient monitoring, location-based emergency response, anomalous daily activity detection, pervasive access to medical data and social networking. CAMPH is aimed to support autonomous physical spaces owned by different organizations, which enables the elderly to
Technological and methodological improvements allow for the study of increasingly complex processes and systems, not least for studying the inner workings of living cells [1,2]. Various detection modalities are used to this end, providing complementary advantages and information for probing and labeling cellular metabolites.
For example, several small-molecule and genetically encoded fluorescent probes are under examination for their potential to measure steady-state concentrations, enzyme activities and resulting intracellular reaction kinetics [1,3]. Other methods include IR [4], UV-Vis, luminescence, Raman [5] and NMR spectroscopy as well as destructive detection by mass spectrometry [2]. The choice of appropriate methods AV-951 requires consideration of the ease of use, commercial availability, sensitivity, biocompatibility, selectivity, spatiotemporal resolution, general applicability, non-invasiveness and quantifiability [1].NMR spectroscopy is a robust, generally applicable and noninvasive method yielding quantifiable and high-resolution spectroscopic data that can distinguish analytes by resolving individual atomic sites. On the other hand, NMR spectroscopy has shortcomings in terms of sensitivity.
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