One graft was deployed 10 mm too proximally, covering the left subclavian artery. No aortic valvular insufficiency or left ventricular dysfunction was noted.
Conclusion: An aortic endograft can be delivered in an antegrade manner transapically into the descending thoracic aorta in a pig model with a reasonable degree of accuracy and minimal hemodynamic compromise. (J Vasc Surg 2008;48:1301-5.)”
“The purpose of this study was to determine whether coil embolisation with a new complex-shaped
Guglielmi Detachable Coil (GDC 360A degrees; Boston Scientific Neurovascular, Fremont, CA, USA) has any effect on the stability of aneurysm occlusion.
Fifty-one consecutive WZB117 clinical trial patients with intracranial aneurysms treated with GDC 360A degrees were included. Angiographic results and adverse neurological events during the follow-up period were recorded. For 38 patients treated with GDC 360A degrees with available follow-up data, a corresponding patient treated with GDC 3D was identified from our database. Matches were
sought for rupture status, location, aneurysmal size, and neck size. The angiographic outcome of these matched controls at 6 months was compared to aneurysms treated with GDC 360A degrees.
Initial angiographic controls for 38 patients treated with GDC 360A degrees showed complete occlusion in 32 aneurysms, and a neck remnant in six. At 6-month selleck compound follow-up, complete occlusion was found in 29, a neck remnant in eight, and a residual aneurysm in one. One patient treated with GDC 360A degrees needed retreatment for a major recanalisation. In 38 matched patients treated with GDC 3D, initial
angiographic controls found complete aneurysmal occlusion in 30 aneurysms and a residual neck in 8. At 6-month follow-up, 24 aneurysms were completely occluded, ten showed a neck remnant, and residual aneurysms were seen in four. Four patients, treated with GDC 3D, were retreated for major aneurysm recanalisations.
Our data suggests that endovascular coil embolisation with GDC 360A degrees might improve long-term stability of coiled aneurysms when compared to GDC 3D.”
“Objective: Persistent endoleak and endotension, complications after endovascular aortic repair, may be caused by an unorganized thrombus inside the aneurysm. The experimental study was designed to evaluate the effectiveness of stent Sclareol grafts (S/Gs) with slow release of basic fibroblast growth factor (bFGF) for the organization.
Methods: The S/Gs were constructed of self-expanding Z stent covered with expanded polytetra fluoroethylene graft, and coated with elastin to be able to bind and slowly release bFGF. Five elastin-coated S/Gs with bFGF (bFGF-S/Gs) and without bFGF (C-S/Gs) were placed in the normal canine aorta respectively. The thoracic aortic aneurysm models were surgically created with a jugular vein patch in 12 beagles. S/Gs with six holes, for creating endoleaks, were used in the experiment of aneurysmal repair. The bFGF-S/Gs (n = 6) and C-S/Gs (n = 6) were implanted.
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