Only Fitzpatrick types II, III and IV were found in the skin phototypes of residents in Hangzhou area, and Fitzpatrick type II seemed to be much more subject to severe wrinkling, elasticity destruction and skin tumors than types III and IV. The oily skin was more protected
against wrinkling and facial looseness than dry skin. However, as to concomitant cutaneous diseases, no difference was found among different skin types.
Age, solar-exposure CP690550 time, Fitzpatrick type and skin type are the associated forces in promoting skin aging, and emotional factor seems to be another independent risk factor. The age of 49 years and 2 h/d of solar-exposure time seem to be the turning points responsible for dramatic changes of cutaneous appearance in the process of skin aging in Southeast China.”
“Background: Emerging data suggest a role for the vitamin D receptor (VDR) in lipogenesis and adipocyte differentiation. Objective: Our objective was to evaluate the association of VDR gene variants and adiposity phenotypes in an epidemiologic study. Design: In a sample of 1773 healthy female adults recruited from western New York, we tested for the association
of 14 VDR single nucleotide NVP-BSK805 polymorphisms (SNPs) with the following 3 adiposity phenotypes: body mass index (in kg/m(2)), waist circumference (in cm), and abdominal height (in cm). We examined age, education, total energy C188-9 in vivo intake, smoking status, alcohol intake, and menopausal status as potential covariates. Results: One SNP, rs3782905, remained associated with all 3 adiposity phenotypes after multiple-testing correction (Bonferroni-adjusted P = 0.004).
The mean waist circumference for women with the rs3782905 homozygous rare genotype was 4.4 cm larger than for women with the common homozygous genotype. Two other VDR SNPs were associated with waist circumference and abdominal height, but the associations did not survive multiple-testing correction. Adjustment for covariates did not influence the results. Conclusion: The study results and the biological activity of VDR in adipocyte differentiation suggest that 3′ VDR variants may play a role in adiposity phenotypes. Am J Clin Nutr 2011;93:5-10.”
“A 62-year-old woman who underwent heart transplantation 6 years later presented a regular atrial tachycardia. Electrophysiologic evaluation showed an atrial arrhythmia in the recipient atrium with 2:1 conduction to the donor atrium, with a confusing electroanatomical map. With the suspect of alternant conduction through two different breakthroughs, the map was split in two concordant maps, corresponding to two connections that were successfully ablated. Later on, a third connection was detected and therefore ablated.
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