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Clin Infect Dis 1999, 29:1128–1132.PubMedCrossRef 35. Mehrotra M, Wang G, Johnson WM: Multiplex PCR for detection of genes forStaphylococcus aureusenterotoxins, exfoliative toxins, toxic shock syndrome toxin1, and methicillin resistance. J Clin Microbiol 2000, 38:1032–1035.PubMed 36. Jarraud S, Cozon G, Vandenesch F, Bes M, Etienne J, Lina G: Involvement of enterotoxins G and I SRT1720 clinical trial in staphylococcal toxic shock syndrome and staphylococcal scarlet fever. J Clin Microbiol 1999, 37:2446–2449.PubMed 37. Enright MC, Day NPJ, Davies CE, Peacock SJ, Spratt

BG: Multilocus sequence typing for characterization of methicillin resistant and methicillin susceptible clones ofStaphylococcus aureus. J Clin Microbiol 2000, 38:1008–1015.PubMed 38. Shopsin B, Gomez M, Montgomery SO, Smith DH, Waddington M, Dodge DE, Bost DA, Riehman M, Naidich S, Kreiswirth BN: Evaluation of protein A gene polymorphic region DNA sequencing for typing ofStaphylococcus aureusstrains. J Clin Microbiol 1999, 37:3556–3563.PubMed

Authors’ contributions SS, SN and SP have done the molecular Ion Channel Ligand Library molecular weight characterization, and helped in organizing tables and figure, MB has planned and executed the microarray, GA has planned the study, executed and drafted the manuscript, JE has helped with microarray and editing the manuscript. All authors have read and approved the manuscript.”
“Background Aeromonads are ubiquitous free-living organisms found in aquatic environments with a strong ability to quickly colonize an exceptionally wide variety of habitats and hosts, ranging from hostile environments, such as polluted or chlorinated water, to leeches, insects, Fossariinae fish, mollusks, and mammals, including man [1]. They are opportunistic pathogens involved in various types of infections in a wide range of hosts. This versatility is supported by a large variety of genes involved in metabolic fitness and virulence; thus, Aeromonas hydrophila

is referred to as a “jack-of-all-trades” [2]. Despite the adaptability of A. hydrophila, very few mobile genetic elements, which are usually associated with rapid adaptation, have been found in the complete genomic sequence of the pathogenic strain A. hydrophila ATCC 7966T[2]. Additionally, because some hosts may only be either colonized or infected, the concept that only specific subsets of Aeromonas strains MAPK inhibitor within species might actually be pathogenic for humans was proposed [3, 4]. In this setting, the question has arisen of whether isolates causing infectious diseases are exceptional and can be distinguished from other strains. Comparative analyses including environmental and clinical isolates showed that clinical strains are well differentiated from strains collected in the environment based on multilocus enzyme electrophoresis (MLEE) [5]. Other studies employing phenotypic, genotypic and virulence analyses have failed to distinguish isolates involved in infectious diseases from those that are not [3, 6–8].

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  5. J Clin Microbiol 1995, 33:1080–1083 PubMed 36 Murrey BE, Singh K
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