Probiotics could
be a reasonable strategy in prevention of antibiotic associated disturbances of the intestinal homeostasis and disorders. buy GSK872 Acknowledgements We thank Manuela Kramp for technical assistance. This work was supported by grants from The Excellence Cluster “”Inflammation at Interfaces”" (funded by the German Research Foundation, DFG) and the Medical Faculty of the Christian-Albrechts-University (CAU) Kiel within the research program “”inflammation medicine”". References 1. Wistrom J, et al.: Frequency of antibiotic-associated diarrhoea in 2462 antibiotic-treated hospitalized patients: a prospective study. J Antimicrob Chemother 2001,47(1):43–50.PubMedCrossRef 2. McDonald LC, Owings M, Jernigan DB: Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996–2003. Emerg Infect Dis 2006,12(3):409–415.PubMedCrossRef 3. Zilberberg MD, Tillotson GS, McDonald C: Clostridium difficile infections among hospitalized children, United States, 1997–2006. Emerg Infect Dis 2010,16(4):604–609.PubMed 4. Kelly CP, LaMont JT: Clostridium difficile-more difficult than ever. N Engl J Med 2008,359(18):1932–1940.PubMedCrossRef 5. Hickson M, et al.: Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo
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