By comparing shingle writing BER bathtub profiles in different writing skew conditions 0 degrees, +/-2 degrees, +/-4 degrees, +/-6 degrees, the effect of varying shingle track asymmetry and curvature is analyzed via subsequent skewed reading process. The shingle writing BER bathtub profiles
as well as the read back amplitude cross track profile are generally symmetric upon one sided erasure at different Quizartinib Angiogenesis inhibitor track pitches. We found that the 0 degrees skew writing and reading process provides both the maximum BER and amplitude. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3559493]“
“Parathyroid carcinoma is a rare endocrine malignancy. The reported incidence is from 0.5 to 5% of primary hyperparathyroidism cases in various series. The cause is unknown, but clinical correlations with different genetic syndromes exist. Mutations in the HPRT2 gene seem to play a significant role in the pathogenesis of this disease. Men and women are equally affected, usually in the fourth or fifth decade of life. Most patients will present with signs and symptoms
of hypercalcaemia. Cases of non-functioning carcinoma are exceedingly rare. Surgical resection is the most effective method of treatment and palliation. A significant proportion of patients will experience recurrence, and will need further surgical and, eventually, medical management of hypercalcaemia. The disease is progressive GSK461364 cell line but slow growing. Most patients will require multiple operations to resect recurrent disease. The main cause of morbidity and mortality is the sequela of uncontrolled chronic hypercalcaemia rather than tumour burden. The current paper will review the epidemiology, pathogenesis, clinical presentation and diagnostic work-up of this disease. Surgical management in different scenarios is reviewed in detail, followed by other types of treatment and management of incurable disease. (C) 2010 The Royal
College of Radiologists. Published by Elsevier Ltd. All rights reserved.”
“New Z-VAD-FMK solubility dmso polymer blends of polypropylene random copolymer (PP-R) and poly(ethylene-octene) (POE) were prepared by melt-blending process using a corotating twin-screw extruder. The POE content was varied up to 35%. The toughening efficiency of POE for PP-R was evaluated by the mechanical properties of the resulted PP-R/POE blends. The crystallization behavior and morphology of the blends were also studied. Results show that POE acts as nucleation agent to induce the crystallization of PP-R matrix at higher crystallization temperature. Super-toughened PP-R/POE blends (Izod impact strength more than 500 J/m) can be readily achieved with only 10 wt % of POE. The high toughness of PP-R/POE is attributed to cavitation and shear yielding of matrix PP-R, as revealed by the morphology studies. (C) 2011 Wiley Periodicals, Inc.
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